Bioinformatics

Bioinformatic Services

• De novo assembly of genomes and transcriptomes
• Mapping to reference genomes and evaluation of variants (SNPs, indels, copy number variations and structural variations)
• Data analysis for Exome Enrichment with detection of genome-wide copy number changes, copy-neutral LOH, SNPs and indels
• Gene expression analysis with read mapping and RPKM/FPKM estimation
• Differential expression analysis of novel and reference transcripts
• Alignment of small RNAs to reference database and pairwise differential expression analysis
• Advanced microbiome data analysis for 16S (V3-V4, V4, V4-V5), 18S and ITS samples (QIIME 2)
  
• Metagenome data analysis – assigning taxonomic labels to short DNA sequences
• SRST2 analysis for presence of STs from an MLST database and/or reference genes from a database of sequences for virulence genes, resistance genes and plasmid replicons